Foods tested include: Almond, Apple, asparagus, aspergillus mix, avocado, banana, barley, beef, black pepper, blueberry, brewers yeast, broccoli, cabbage, cacao, cantaloupe, carrot, casein (milk protein), cauliflower, celery, cherry, chicken, cinnamon, clam, coconut, codfish, coffee, corn, cottonseed (vegetable oil), cow's milk, crab, cucumber, egg albumin, egg yolk, walnut, flaxseed, flounder, garlic, ginger, gluten protein, goats milk, grapefruit, grapes, green olive, green pea, green pepper, halibut, honeydew, hops, kidney bean, lemon, lettuce, lima bean, lobster, mushroom, mustard, navy bean, oat, onion, orange, peach, peanut, pear, pecan, pineapple, plum, pork, rice, rye, salmon, scallops, sesame, shrimp, soybean, spinach, strawberry, string bean, sweet potato, tea (black), tomato, tuna, turkey, vanilla bean, watermelon, white potato, whole wheat, yellow squah.
Ige, IgG & C3D
IgG4 is a unique antibody. Firstly distinguished by it’s small size compared to IgG1-3, and by it’s higher level of disulfide bonds. It also has its own distinct activity.
IgG4 is important in relation to IgE because it can act as a blocking agent for an IgE reaction, reducing anaphylaxis and the symptoms mediated by IgE, although, if too high it can also result in a secondary set of conditions of its own.
When the IgG4 reaction is greater than the IgE reaction for a particular antigen, IgG4 can block the IgE antibodies from binding to the receptor sites that would encourage the release of histamine, thereby reducing severity of the symptoms associated with the IgE reaction. This is referred to as the ‘blocking potential’, which is displayed on the report.
IgG (Immunoglobulin G, total)
IgG are antibodies that provide long-term resistance to infections and have a much longer half-life than the traditional IgE allergy. The IgG antibody response creates sensitivity to a particular food. Symptoms may be less severe than with IgE allergic reaction and can manifest anywhere from 3-72 hours after exposure. The delayed response makes sensitivities difficult to identify without a test.
IgG reactions create inflammation that makes many pathologies worse. Sensitivity symptoms range from headache and nausea to seizure and hyperactivity, or simply just fatigue, bloating, mood changes, or dark circles under the eyes. Sensitivities can improve with treatment and improved gut health.
C3d (Complement component 3)
The Dietary Antigen Test (IgG with Complement) measures Complement activation for multiple foods. Complement activation is well-defined in the research as not only a cause of inflammation but one of the strongest causes.
C3d is an activator of the Complement cascade system. Reaction to the specified food will worsen if C3d activation is present along with an IgG antibody response.
When C3d is activated in response to an antigen, the C3 portion attaches to the antigen. This activation, even though it is independent, will amplify the reaction that occurs with total IgG greatly increasing inflammation and symptoms of sensitivity.
What is the C3d Pathway?
The Complement pathway acts as the body’s SWAT team to aggressively attack and clear threats, such as bacteria, viruses, protozoa, and allergens. It is part of the innate immune system, meaning that we are born with this immune defense mechanism.
Complement components patrol the blood harmlessly, but in an instant can go on the attack to kill and remove dangerous molecules from the body. When activated, the Complement pathway sets off a domino effect of inflammatory cytokines, mast cell degranulation (Histamine), and cell membrane destruction. It is a powerful protective force but can damage tissues if not kept under control.
Complement is a quantifiable, reliable biomarker of tissue inflammation.
information is written from https://rnlabs.com.au/functional-tests/precision-allergy-88/
Currently only available in Australia & USA.